N Ke, HW Ma, G Diedrich, J Chionis, GH Liu, DH Yu, F. Wong-Staal, QX Li   2008. Biochemical characterization of genetic mutations of GRP56 in patients with bilateral frontoparietal polymicrogyria (BFPP).  Biochemical and Biophysical Research Communications. In press.

N Ke, R Sundaram, GH Liu, J Chionis, WF Fan, C Rogers, T Awad, M Grifman, DH Yu, F Wong-Staal, and QX Li . 2007. Orphan G-protein coupled receptor GPR56 plays a role in cell transformation and tumorigenesis involving the cell adhesion pathway. Molecular Cancer Therapeutics. 6:1840-1850.

GH Liu, M Grifman, JM Macdonald, P Moller, F Wong-Staal, QX Li, 2007. Isoginkgetin enhances adiponectin secretion from differentiated adiposarcoma cells via a novel pathway involving AMPK. Journal of Endocrinology. 194:569-5

J Zhang, CY Wang, N Ke, J. Bliesath, J. Chionis, QS He, QX Li, JE. Chatterton, F Wong-Staal and DM Zhou. 2007. Novel Tetracycline-Off RNAi Inducible System for Tight Regulation of Gene Expression in Mammalian Cells and Xenograft Animals. RNA. 13:1375-1383. 78.

Liu G, Wong-Staal F, Li QX 2006 Rent development of RNAi in drug target discovery and validation. Drug Discovery Today, 3:293-300, 96:103-43.

GH Liu, F Wong-Staal, QX Li. Development of RNAi therapeutics. 2007. Histology and Histopathology. Cellular and Molecular Biology. 22:211-217,

Ke N, Zhou D, Chatterton JE, Liu GH, Chionis J, Zhang J, Tsugawa L, Lynn R, Yu D, Meyhack D, Wong-Staal F, Li Q-X A new inducible RNAi xenograft model for assessing the staged tumor response to mTOR silencing. Experimental Cell Research. 312: 2726-2734, 2006.

Yu DH, Macdonald JM, Josephs S, Liu Q, Nguy V, Tor Y, Wong-Staal F, Li Q-X 2006. MDDD, a 4,9-diazapyrenium derivative, is selectively toxic to glioma cells by inducing growth arrest at G0/G1 independently of p53. Investigational New Drug. 24(6): 489-98

Yu DH, Fan WF, Liu GH, Nguy V., Chatterton JE, Long S, Ke N, Meyhack B, Bruengger A, Brachat A, Wong-Staal F, Li QX. 2006 PHTS, a novel putative tumor suppressor gene, is involved in the transformation reversion of HeLaHF cells independently of the p53 pathway. Experimental Cell Research. 312:865-876

Li QX, Ke N., Sundaram R, Wong-Staal F  2006 NR4A1, 2, 3 – an orphan nuclear hormone receptor family involved in cell apoptosis and carcinogenesis. Histology and Histopathology. Cellular and Molecular Biology. 21:533-540

Yang JP, Fan WF, Rogers C, Chatterton JE, J Bliesath J, Liu GH, Ke N, Wang CY, Rhoades K, Wong-Staal F, Li QX 2006 A novel RNAi library based on partially randomized consensus sequences of nuclear receptors: identifying the receptors involved in Amyloid β degradation. Genomics. 88: 282-292.

Liu GH, Grifman M, Keily B, Chatterton JE, Wong-Staal F, Li QX  2006 Mineralocorticoid receptor is involved in the regulation of genes responsible for hepatic glucose production. Biochemical and Biophysical Research Communications. 342(4):1291-6

Zhou DM, He QS, Wang C, Wong-Staal F. 2006 NA interference and potential applications. Current Topics in Medicinal Chemistry. 6:901-911.

Li Q-X, Tan P, Ke N, Wong-Staal F.  Ribozyme Technolgoy and its applications in cancer gene target identification and validation.  In - Advances in Cancer Research, Volume 96 Chapter 4, Eds. G. Hampton and K. Silkora. Academic Press.  96:103-43. 2006

Long S, Troung L, Bennett K, Phillips A., Wong-Staal F, Ma H. Expression, purification, and renaturation of bone morphogenetic protein-2 from Escherichia coli. Protein Expression & Purification. 46::374-378. 2006

DH Yu, JE Chatterton, JR Bliesath, N Ke, V Nguy, B Meyhack, F Wong-Staal, Qi-Xiang Li. 2005. A 96-well surrogate survival assay coupled with a special short interfering RNA vector for assessing cancer gene targets with enhanced signal/noise ratio and its utility in HTS for cacner therapeutic targets. Assay Drug Dev Technol., 3(4): 401-411

Ke N, Claassen G, Yu DH, Albers A, Fan W, Tan P, Grifman M, Hu X, Defife K, Nguy V, Meyhack B, Brachat A, Wong-Staal F, Li Q-X. 2004 Nuclear hormone receptor NR4A2 is involved in cell transformation and apoptosis. Cancer Reseach 15;64(22):8208-12.

Ke N, Albers A, Claassen G, Yu DH, Chatterton JE, Hu X, Meyhack B, Wong-Staal F, Li QX 2004 One-week 96-well soft agar growth assay for cancer target validation. Biotechniques. 36(5):826-8, 830, 832-3.

Waninger S, Kuhen K, Hu X, Chatterton JE, Wong-Staal F, Tang H 2004 Identification of cellular cofactors for human immunodeficiency virus replication via a ribozyme-based genomics approach. J Virol. 78(23):12829-37.

G Claassen, N Ke, D Yu, JE Chatterton, XY Hu, A Albers, V Nguy, J Chionis, T Truong, B Meyhack, F Wong-Staal, QX Li. 2004.Comprehensive assessment of cell growth properties affected by various agents using an integrated and non-subjective approach. Preclinica 2: 435-439,

Ma H, Thibault J, Lu Y, Whiting C, Long S, Lindwall G, Bennett K, Truong L, Aimes RT, Wong-Staal F. 2004 The development and applications of nonradioactive plate-formatted DNA-binding assay for Ku70/80, a multifunctional DNA-binding protein complex. Assay Drug Dev Technol. 2(5):483-95.

Hu X, Hipolito S, Lynn R, Abraham V, Ramos S, Wong-Staal F. 2004 Relative gene-silencing efficiencies of small interfering RNAs targeting sense and antisense transcripts from the same genetic locus. Nucleic Acids Res. 27;32(15):4609-17.

Chatterton, JE, Hu, XY, Wong-Staal, F, 2004Ribozymes in gene identification,target validation and drug discovery  Targets, Vol.3, No.1

LN Pierce, PK Tan, QX Li, and F. Wong-Staal, 2003Inverse Genomics: A Gene Discovery Platform Based on Inactivation of Gene Expression, in Perspectives in Gene Expression, ed. Krishnarao Appasani

Habita, C, Gutenberg, P, Alspaugh, E, Houston, B, Zerouala, C, Barber, JR, Robbins, J, Safety Evaluation of Proliferating Cell Nuclear Antigen Targeted Ribozyme to Inhibit Cell Proliferation in Proliferative Vitreoretinopathy. Preclinica, March/April 2003, Vol. 1, No. 1.

Rhoades, K. and Wong-Staal, F. Inverse genomics as a powerful tool to identify novel targets for the treatment of neurodegenerative diseases. 2003. Mechanisms of Ageing and Development. 124 (1); 125-132.  

Mandava, N, Blackburn, P, Paul, DB, Wilson, MW, Read, SB, Alspaugh, E, Tritz, R, Barber, JR, Robbins, JM, Kruse, CA., Ribozyme to proliferating cell nuclear antigen to treat proliferative vitreoretinopathy. Investigative Ophthalmology & Visual Science, October 2002, Vol. 43, No. 10.

DeFife, KM, Wong-Staal, F. Integrated approaches to therapeutic target gene discovery. Current Opinion in Drug Discovery and Development 2002 5(5): 683-689.

Rhoades, KL, Chatterton, JE, Wong-Staal, F. 2002, Inverse Genomics®: Application of ribozyme technology to high-throughput gene discovery. In: Gene Cloning and Expression Technologies, 493-510. Eaton Publishing

Tang, H, Peng, T, Wong-Staal, F. 2002, Novel technologies for studying virus-host interaction and discovering new drug targets for HCV and HIV. Current Opinion In Pharmacology 2:541-547.

Tang, H., He, S, Kuhen, K, Barber, JR, Wong-Staal, F. Institute of Human Virology. (2001 International Meeting of the Institute of Human Virology Baltimore, Maryland, USA September 09-13, 2001). Selection of hairpin ribozymes that confer HIV resistance to T cells in vitro. In: Journal of Human Virology May-June, 2001. 4 (3): 128.

Krueger, M., Beger, C., Welch, P.J., Barber, J.R., Manns, M.P., Wong-Staal, F. Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation. In: Molecular and Cellular Biology December, 2001. 21 (24): 8357-8364.

Leavitt, MC, Yu,G, Zhou,C, and Barber,JR Inhibition of interleukin 1beta(IL-1beta) production in human cells by ribozymes against IL-1beta and IL-1 beta converting enzyme (ICE). Antisense Nucl Acid Drug Dev. 2000 Dec;10(6):409-14.PMID:11198924, 2001.

Beger, C, Pierce, LN, Kruger, M, Marcusson, EG, Robbins, JR Welcsh, P, Welch PJ, Welte, K., King, MC, Barber, JR, and Wong-Staal, F. 2001. Identification of Id4 as a regulator of BRCA-1 expression using a ribozyme-library based inverse genomics® approach. Proc. Natl Acad. Sci., USA 98, 130-135

Beger, C, Pierce, LN, Kruger, M, Marcusson, EG, Robbins, J.R, Welte, K, Barber, JR, Wong-Staal, F. American Society of Hematology. (42nd Annual Meeting of the American Society of Hematology San Francisco, California, USA December 01-05, 2000). Identification of genes regulating BRCA1 expression using a ribozyme-library based functional genomics approach. In: Blood November 16, 2000. 96 (11 Part 2): 171b.

Wong-Staal, F, Kruger, M, Beger, C, Tang, H., Kuhen, K., Tritz, R., Robbins, J. R., Barber, J. R. 2000 International Meeting of the Institute of Human Virology Baltimore, Maryland, USA September 10-15,2000). An inverse genomics® approach for gene discovery for hepatitis, cancer and AIDS. In Journal of Human Virology September-October, 2000. 3 (5): 237.

Feng, Y., Leavitt, M., Tritz,R., Duarte, E., Kang,D., Mamounas, M., Gilles,P., Wong-Staal,F., Kennedy,S., Merson, J., Yu, M., and Barber, J.R. 2000. Inhibition of CCR5-dependent HIV-1 infection by ribozymes against CC-chemokine receptor 5. Virology 276, 271-278,

Kruger M, Beger C, Li QX, Welch PJ, Tritz R, Leavitt M, Barber JR, Wong-Staal F. 2000. Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach. Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8566-71. PMID: 10900014; UI: 20359747

Welch PJ, Marcusson EG, Li QX, Beger C, Kruger M, Zhou C, Leavitt M, Wong-Staal F, Barber JR. 2000 Identification and validation of a gene involved in anchorage-independent cell growth control using a library of randomized hairpin ribozymes. Genomics. 2000 Jun 15;66(3):274-83 PMID: 10873382; UI: 20334623,.

Li, QX, Robbins, JR, Welch, PJ, Wong-Staal, F, and Barber, JR. 2000  A novel functional genomics approach identifies mTERT as a supressor of fibroblast transformation. Nuc. Acids Res., 28, 2605-2612